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حسن علي البط (talk | contribs) |
add drug class infobox parameter |
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{{Short description|Drug for functional gastrointestinal disorders}}
{{Refimprove|date=March 2009}}
{{Drugbox
| Verifiedfields = changed
| verifiedrevid = 464216255
| IUPAC_name = ''N''-isopropyl-''N''-methyl-''N''-<nowiki/>{2-[(9''H''-xanthen-9-ylcarbonyl)oxy]ethyl}propan-2-aminium bromide▼
| image = Proprantheline bromide.svg▼
<!--Clinical data-->
| tradename =
| Drugs.com = {{drugs.com|monograph|propantheline_bromide}}
| MedlinePlus = a684020
| pregnancy_AU = <!-- A / B1 / B2 / B3 / C / D / X -->▼
| pregnancy_US = <!-- A / B / C / D / X -->▼
| legal_AU = <!-- Unscheduled / S2 / S4 / S8 -->▼
| legal_UK = <!-- GSL / P / POM / CD -->▼
| legal_US = <!-- OTC / Rx-only -->▼
| class = [[Antimuscarinic]]
<!--Identifiers-->
| CAS_number_Ref = {{cascite|correct|CAS}}
▲|image = Proprantheline bromide.svg
▲|IUPAC_name = ''N''-isopropyl-''N''-methyl-''N''-{2-[(9''H''-xanthen-9-ylcarbonyl)oxy]ethyl}propan-2-aminium bromide
| ATC_prefix = A03▼
▲|CAS_number=298-50-0
| ATC_suffix = AB05▼
| PubChem = 9279▼
▲|ATC_prefix=A03
| IUPHAR_ligand = 329
▲|ATC_suffix=AB05
| DrugBank_Ref = {{drugbankcite|changed|drugbank}}
▲|PubChem = 9279
| DrugBank =
| ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}}
|C=23|H=30|N=1|O=3▼
| ChemSpiderID = 8922
| UNII_Ref = {{fdacite|correct|FDA}}
| UNII = UX9Z118X9F
| ChEMBL_Ref = {{ebicite|correct|EBI}}
| ChEMBL = 1240
| KEGG_Ref = {{keggcite|changed|kegg}}
| KEGG = D00481
▲|pregnancy_AU=<!-- A / B1 / B2 / B3 / C / D / X -->
<!--Chemical data-->
▲|pregnancy_US=<!-- A / B / C / D / X -->
▲| C=23 | H=30 | N=1 | O=3
| smiles = [Br-].O=C(OCC[N+](C(C)C)(C(C)C)C)C2c3c(Oc1c2cccc1)cccc3
▲|legal_AU=<!-- Unscheduled / S2 / S4 / S8 -->
| StdInChI_Ref = {{stdinchicite|correct|chemspider}}
▲|legal_UK=<!-- GSL / P / POM / CD -->
| StdInChI = 1S/C23H30NO3.BrH/c1-16(2)24(5,17(3)4)14-15-26-23(25)22-18-10-6-8-12-20(18)27-21-13-9-7-11-19(21)22;/h6-13,16-17,22H,14-15H2,1-5H3;1H/q+1;/p-1
▲|legal_US=<!-- OTC / Rx-only -->
| StdInChIKey_Ref = {{stdinchicite|correct|chemspider}}
| StdInChIKey = XLBIBBZXLMYSFF-UHFFFAOYSA-M
}}
'''Propantheline bromide''' ([[International Nonproprietary Name|INN]]) is an [[antimuscarinic]] agent used for the treatment of excessive sweating ([[hyperhidrosis]]), cramps or spasms of the stomach, intestines (gut) or bladder, and involuntary urination ([[enuresis]]). It can also be used to control the symptoms of [[irritable bowel syndrome]] and similar conditions. This agent can also be used for patients who experience intense GI symptoms while tapering off of [[Tricyclic antidepressant|TCAs]].
<ref>{{ ==Indications==
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==Adverse effects==
[[Adverse drug reaction|Side effects]] include [[tachycardia]], [[constipation]], [[photophobia|hypersensitivity to light]], dry mouth, and [[urinary retention]].
This can also be prescribed by dentists for certain patients who salivate excessively. By
==Mechanism of action==
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==References==
{{
{{Drugs for functional gastrointestinal disorders}}
{{Muscarinic acetylcholine receptor modulators}}
[[Category:Muscarinic antagonists]]
[[Category:Quaternary ammonium compounds]]
[[Category:Bromides]]
[[Category:Carboxylate esters]]
[[Category:Xanthenes]]
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