Carboxypeptidase A6

CPA6
Identifiers
Aliases	CPA6, CPAH, ETL5, FEB11, carboxypeptidase A6
External IDs	OMIM: 609562; MGI: 3045348; HomoloGene: 75130; GeneCards: CPA6; OMA:CPA6 - orthologs
Gene location (Human)
Chr.	Chromosome 8 (human)
End	67,746,378 bp
Gene location (Mouse)
Chr.	Chromosome 1 (mouse)
End	10,790,170 bp
RNA expression pattern
	Top expressed in
	buccal mucosa cell; ; mucosa of transverse colon; ; urethra; ; rectum; ; epithelium of colon; ; prostate; ; vagina; ; tibia; ; mucosa of sigmoid colon; ; smooth muscle tissue;
	Top expressed in
	otolith organ; ; utricle; ; calvaria; ; lumbar subsegment of spinal cord; ; tail of embryo; ; spermatid; ; inferior olivary nucleus; ; belly cord; ; seminiferous tubule; ; stroma of bone marrow;
	More reference expression data
	n/a
Gene ontology
Molecular function	carboxypeptidase activity; zinc ion binding; peptidase activity; hydrolase activity; metallopeptidase activity; metal ion binding; metallocarboxypeptidase activity;
Cellular component	extracellular region; extracellular space;
Biological process	proteolysis;
	Sources:Amigo / QuickGO
Orthologs
	57094
	329093
	ENSG00000165078
	ENSMUSG00000042501
	Q8N4T0
	Q5U901
	NM_001127445; NM_020361
	NM_001289497; NM_177834
	NP_065094
	NP_001276426; NP_808502
	Wikidata
View/Edit Human	View/Edit Mouse

Carboxypeptidase A6 is an enzyme that in humans is encoded by the CPA6 gene.^[5]

The protein encoded by this gene belongs to the family of carboxypeptidases, which catalyze the release of C-terminal amino acid, and have functions ranging from digestion of food to selective biosynthesis of neuroendocrine peptides. Polymorphic variants and a reciprocal translocation t(6;8)(q26;q13) involving this gene, have been associated with Duane retraction syndrome.[provided by RefSeq, Sep 2010].^[5]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000165078 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000042501 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ ^a ^b "Entrez Gene: Carboxypeptidase A6". Retrieved 2011-11-25T03:01:34.724-08:00. {{cite web}}: Check date values in: |accessdate= (help)

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