Small RNA binding exonuclease protection factor La (Q21133460)

From Wikidata

Jump to navigation Jump to search

mammalian protein found in Homo sapiens

SS-B/La protein
La ribonucleoprotein domain family, member 3
lupus La antigen
SSB
La ribonucleoprotein
la autoantigen
autoantigen La
Sjogren syndrome antigen B
SS-B
sjoegren syndrome type B antigen
lupus La protein

Language	Label	Description	Also known as
English	Small RNA binding exonuclease protection factor La	mammalian protein found in Homo sapiens	SS-B/La protein La ribonucleoprotein domain family, member 3 lupus La antigen SSB La ribonucleoprotein la autoantigen autoantigen La Sjogren syndrome antigen B SS-B sjoegren syndrome type B antigen lupus La protein

Statements

1 reference

13 November 2019

UniProt protein ID

winged helix DNA-binding domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P05455

RNA-binding domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P05455

Winged helix-like DNA-binding domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P05455

Lupus La protein

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P05455

Nucleotide-binding alpha-beta plait domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P05455

La-type HTH domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

La protein, RNA-binding domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

RNA recognition motif domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

molecular function

protein binding

determination method

3 references

8 April 2019

A combined proteomics/genomics approach links hepatitis C virus infection with nonsense-mediated mRNA decay

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05455

determination method

8 April 2019

Human La protein interaction with GCAC near the initiator AUG enhances hepatitis C Virus RNA replication by promoting linkage between 5' and 3' untranslated regions

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05455

determination method

8 April 2019

Host factors that interact with the pestivirus N-terminal protease, Npro, are components of the ribonucleoprotein complex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05455

determination method

determination method

1 reference

8 April 2019

Human La protein: a stabilizer of histone mRNA

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05455

determination method

nucleic acid binding

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05455

determination method

determination method

determination method

6 references

26 September 2017

Genomic structure and amino acid sequence domains of the human La autoantigen

Critical Assessment of Protein Function Annotation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P05455&geneProductId=UniProtKB:P05455

determination method

26 September 2017

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P05455&geneProductId=UniProtKB:P05455

determination method

26 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P05455&geneProductId=UniProtKB:P05455

determination method

26 September 2017

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=P05455&geneProductId=UniProtKB:P05455

determination method

26 September 2017

The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P05455&geneProductId=UniProtKB:P05455

determination method

26 September 2017

Insights into RNA biology from an atlas of mammalian mRNA-binding proteins

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P05455&geneProductId=UniProtKB:P05455

determination method

poly(U) RNA binding

determination method

3 references

8 April 2019

Structural basis for recognition and sequestration of UUU(OH) 3' temini of nascent RNA polymerase III transcripts by La, a rheumatic disease autoantigen

Critical Assessment of Protein Function Annotation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05455

determination method

8 April 2019

Structural analysis of cooperative RNA binding by the La motif and central RRM domain of human La protein

Critical Assessment of Protein Function Annotation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05455

determination method

8 April 2019

Structure of the C-terminal domain of human La protein reveals a novel RNA recognition motif coupled to a helical nuclear retention element

Critical Assessment of Protein Function Annotation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05455

determination method

protein homodimerization activity

determination method

1 reference

8 April 2019

Structure of the C-terminal domain of human La protein reveals a novel RNA recognition motif coupled to a helical nuclear retention element

Critical Assessment of Protein Function Annotation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05455

determination method

sequence-specific mRNA binding

determination method

1 reference

8 April 2019

Human La protein: a stabilizer of histone mRNA

Critical Assessment of Protein Function Annotation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05455

determination method

determination method

6 references

8 April 2019

Genomic structure and amino acid sequence domains of the human La autoantigen

Critical Assessment of Protein Function Annotation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05455

determination method

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05455

determination method

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05455

determination method

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05455

determination method

8 April 2019

The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05455

determination method

8 April 2019

Insights into RNA biology from an atlas of mammalian mRNA-binding proteins

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05455

determination method

determination method

5 references

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05455

determination method

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05455

determination method

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05455

determination method

8 April 2019

Conservation of a masked nuclear export activity of La proteins and its effects on tRNA maturation

Critical Assessment of Protein Function Annotation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05455

determination method

8 April 2019

Host factors that interact with the pestivirus N-terminal protease, Npro, are components of the ribonucleoprotein complex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05455

determination method

determination method

1 reference

8 April 2019

Conservation of a masked nuclear export activity of La proteins and its effects on tRNA maturation

Critical Assessment of Protein Function Annotation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05455

determination method

biological process

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05455

determination method

histone mRNA metabolic process

determination method

1 reference

8 April 2019

Human La protein: a stabilizer of histone mRNA

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05455

determination method

protein localization to cytoplasmic stress granule

determination method

1 reference

8 April 2019

Host factors that interact with the pestivirus N-terminal protease, Npro, are components of the ribonucleoprotein complex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05455

determination method

tRNA modification

determination method

1 reference

8 April 2019

Control of transfer RNA maturation by phosphorylation of the human La antigen on serine 366

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05455

determination method

IRES-dependent viral translational initiation

determination method

1 reference

8 April 2019

La autoantigen is required for the internal ribosome entry site-mediated translation of Coxsackievirus B3 RNA.

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05455

determination method

tRNA 5'-leader removal

determination method

1 reference

8 April 2019

Control of transfer RNA maturation by phosphorylation of the human La antigen on serine 366

Critical Assessment of Protein Function Annotation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05455

determination method

tRNA export from nucleus

determination method

1 reference

8 April 2019

Conservation of a masked nuclear export activity of La proteins and its effects on tRNA maturation

Critical Assessment of Protein Function Annotation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05455

determination method

tRNA processing

determination method

1 reference

8 April 2019

Conservation of a masked nuclear export activity of La proteins and its effects on tRNA maturation

Critical Assessment of Protein Function Annotation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05455

determination method

tRNA 3'-end processing

determination method

1 reference

8 April 2019

Control of transfer RNA maturation by phosphorylation of the human La antigen on serine 366

Critical Assessment of Protein Function Annotation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05455

determination method

nuclear histone mRNA catabolic process

determination method

1 reference

8 April 2019

Human La protein: a stabilizer of histone mRNA

Critical Assessment of Protein Function Annotation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05455

determination method

La-type HTH domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P05455

La protein, RNA-binding domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P05455

RNA recognition motif domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P05455

Identifiers

RefSeq protein ID

1 reference

30 May 2020

1 reference

30 May 2020

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

Ensembl protein ID

ENSP00000260956

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000260956

ENSP00000386636

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000386636

ENSP00000395758

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000395758

ENSP00000396890

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000396890

ENSP00000397029

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000397029

PDB structure ID

1 reference

UniProt protein ID

4 August 2016

language of work or name

1 reference

UniProt protein ID

4 August 2016

language of work or name

1 reference

UniProt protein ID

4 August 2016

language of work or name

1 reference

UniProt protein ID

4 August 2016

language of work or name

1 reference

UniProt protein ID

4 August 2016

language of work or name

1 reference

UniProt protein ID

4 August 2016

language of work or name

1 reference

UniProt protein ID

4 August 2016

language of work or name

1 reference

UniProt protein ID

4 August 2016

language of work or name

1 reference

UniProt protein ID

4 August 2016

language of work or name

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q21133460&oldid=2023020280"